Guts UK-BSPGHAN Grant Round 2019 - Successful applications
Dr Paul Henderson (IBD)
Institution: University of Edinburgh
Title: The PINPOINT study -The Prospective Incidence of Paediatric-Onset Inflammatory bowel disease in the United Kingdom
Project Start Date: 1 October 2019 Completion Date: 31 December 2020
Professor Matthias Zilbauer (IBD)
Institution: University of Cambridge
Title: Stratification of inflammatory bowel disease treatment in children using human intestinal organoid derived epigenetic signatures
Project Start Date: 1 October 2019 Completion Date: 30 September 2020
Previous BSPGHAN and Guts UK (previously Core) Awards 2017 BSPGHAN and Guts (previously Core) https://gutscharity.org.uk/ co-funded a scheme to support the collection of pilot or proof-of-concept data that will enable a high-quality competitive application to be made subsequently to a research council or other large funder.
Stephen Allen, Julian Thomas, Simon Murch and Sarah Moule from the Research Working Group joined colleagues from CORE to assess the research submissions. We were impressed by the high standard of all proposals and breadth of topics covered. All proposals were scored individually in advance of the panel meeting and five were selected for detailed review.
The following two projects were supported:
Chris Probert, Professor of Gastroenterology; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool.
"Characterization of the gut mycobiome in an inception cohort of paediatric inflammatory bowel disease"
Sarah Ennis, Professor of Genomics, Genomic Informatics Group Lead, University Hospital Southampton.
"Metabolo-genomic interactions in paediatric Crohn's Diease"
We look forward to receiving feedback as these projects progress. More information about Guts UK is available from https://gutscharity.org.uk/
BSPGHAN/CORE Awards 2015
Stephen Allen and Julian Thomas joined colleagues from CORE to assess 7 submitted proposals. The proposals were of a high standard and were discussed in detail and scored individually by each member of the panel. Although the original budget was £80,000 (with equal contributions from BSPGHAN and CORE), the proposals were considered to be of sufficient quality to include an underspend from a previous award. As a result, a total of £105,987 was awarded to the following 3 successful applicants (with details available from the CORE website):
Dr Emer Fitzpatrick King’s College London
“LiverMultiScanTM for the assessment of graft fibrosis in children post-liver transplant”
Prof David Wilson Child Life and Health, University of Edinburgh; Paediatric Gastroenterology, Royal Hospital for Sick Children, Edinburgh
“Health informatics research in paediatric gastroenterology: nationwide data-linkage exploration of perinatal risk factors for and consequences of paediatric-onset Inflammatory Bowel Disease”
Dr Gordon Moran Nottingham Digestive Diseases Centre, University of Nottingham
“Anabolic resistance and abnormal muscle function across the nutritional spectrum: a pilot study in Crohn's disease and non-alcoholic fatty-liver disease”